Also known as Danoprox, Daypro, Dayrun, Deflam, Duraprox, Oxaprozina, Oxaprozine, Oxaprozinum, Walix, Wy 21743
A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04)
Originator: NCI Thesaurus | Source: The website of the National Cancer Institute (http://www.cancer.gov)
Can I take Oxaprozin while breastfeeding?
Because there is no published experience with oxaprozin during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Drug levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in breastfed infants
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Possible effects on lactation
Relevant published information was not found as of the revision date.
Alternate drugs to consider
Flurbiprofen, Ibuprofen, Piroxicam
References
Last Revision Date
20150310
Disclaimer:Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
Source: LactMed – National Library of Medicine (NLM)